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A Bicyclic Peptide Scaffold Promotes Phosphotyrosine Mimicry and Cellular Uptake

While peptides are promising as probes and therapeutics, targeting intracellular proteins will require greater understanding of highly structured, cell-internalized scaffolds. We recently reported BC1, an 11-residue bicyclic peptide that inhibits the Src homology 2 (SH2) domain of growth factor rece...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Bioorg Med Chem
Egile Nagusiak: Quartararo, Justin S., Eshelman, Matthew R., Peraro, Leila, Yu, Hongtao, Baleja, James D., Lin, Yu-Shan, Kritzer, Joshua A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254597/
https://ncbi.nlm.nih.gov/pubmed/25438762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.09.050
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