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Peptide Bicycles that Inhibit the Grb2 SH2 Domain
Developing short peptides into useful probes and therapeutic leads remains a difficult challenge. Structural rigidification is a proven method for improving the properties of short peptides. In this work, we report a strategy for stabilizing peptide macrocycles by introducing side-chain-to-side-chai...
में बचाया:
| मुख्य लेखकों: | , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3516885/ https://ncbi.nlm.nih.gov/pubmed/22689355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201200175 |
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