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A Bicyclic Peptide Scaffold Promotes Phosphotyrosine Mimicry and Cellular Uptake
While peptides are promising as probes and therapeutics, targeting intracellular proteins will require greater understanding of highly structured, cell-internalized scaffolds. We recently reported BC1, an 11-residue bicyclic peptide that inhibits the Src homology 2 (SH2) domain of growth factor rece...
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| Publicat a: | Bioorg Med Chem |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4254597/ https://ncbi.nlm.nih.gov/pubmed/25438762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.09.050 |
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