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Phosphotyrosine Isosteres: Past, Present and Future

Tyrosine phosphorylation is a critical component of signal transduction for multicellular organisms, particularly for pathways that regulate cell proliferation and differentiation. While tyrosine kinase inhibitors have become FDA-approved drugs, inhibitors of the other important components of these...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Cerulli, Robert A., Kritzer, Joshua A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7233463/
https://ncbi.nlm.nih.gov/pubmed/31777907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9ob01998g
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