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PGE(2) Reduces MMP-14 and Increases Plasminogen Activator Inhibitor-1 in Cardiac Fibroblasts
Prostaglandin E2 (PGE(2)) is elevated during cardiac injury and we have previously shown that mice lacking the PGE EP4 receptor display dilated cardiomyopathy (DCM) with increased expression of the membrane type matrix metalloproteinase, MMP-14. We thus hypothesized that PGE(2) regulates expression...
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| Publicado no: | Prostaglandins Other Lipid Mediat |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4254138/ https://ncbi.nlm.nih.gov/pubmed/25263346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2014.09.002 |
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