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Evidence for the Involvement of MMP14 in MMP2 Processing and Recruitment in Exosomes of Corneal Fibroblasts

PURPOSE: Matrix metalloproteinase (MMP) 14 has been shown to promote angiogenesis, but the underlying mechanisms are poorly understood. In this study, we investigated exosomal transport of MMP14 and its target, MMP2, from corneal fibroblasts to vascular endothelial cells as a possible mechanism gove...

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Détails bibliographiques
Publié dans:Invest Ophthalmol Vis Sci
Auteurs principaux: Han, Kyu-Yeon, Dugas-Ford, Jennifer, Seiki, Motoharu, Chang, Jin-Hong, Azar, Dimitri T.
Format: Artigo
Langue:Inglês
Publié: The Association for Research in Vision and Ophthalmology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538964/
https://ncbi.nlm.nih.gov/pubmed/25015352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14417
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