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Evidence for the Involvement of MMP14 in MMP2 Processing and Recruitment in Exosomes of Corneal Fibroblasts

PURPOSE: Matrix metalloproteinase (MMP) 14 has been shown to promote angiogenesis, but the underlying mechanisms are poorly understood. In this study, we investigated exosomal transport of MMP14 and its target, MMP2, from corneal fibroblasts to vascular endothelial cells as a possible mechanism gove...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Han, Kyu-Yeon, Dugas-Ford, Jennifer, Seiki, Motoharu, Chang, Jin-Hong, Azar, Dimitri T.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538964/
https://ncbi.nlm.nih.gov/pubmed/25015352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14417
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