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Fibroblast MMP14-Dependent Collagen Processing Is Necessary for Melanoma Growth

SIMPLE SUMMARY: Matrix metalloproteinases (MMPs) were considered as targets for the treatment of various cancers. However, initial trials using broad inhibitors to MMPs have failed, partly attributed to the contrasting functions of these proteases acting as tumor promoters and suppressors, among oth...

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Bibliografske podrobnosti
izdano v:Cancers (Basel)
Main Authors: Pach, Elke, Brinckmann, Jürgen, Rübsam, Matthias, Kümper, Maike, Mauch, Cornelia, Zigrino, Paola
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074311/
https://ncbi.nlm.nih.gov/pubmed/33924099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13081984
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