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Fibroblast MMP14-Dependent Collagen Processing Is Necessary for Melanoma Growth

SIMPLE SUMMARY: Matrix metalloproteinases (MMPs) were considered as targets for the treatment of various cancers. However, initial trials using broad inhibitors to MMPs have failed, partly attributed to the contrasting functions of these proteases acting as tumor promoters and suppressors, among oth...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Pach, Elke, Brinckmann, Jürgen, Rübsam, Matthias, Kümper, Maike, Mauch, Cornelia, Zigrino, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074311/
https://ncbi.nlm.nih.gov/pubmed/33924099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13081984
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