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Fibroblast MMP14-Dependent Collagen Processing Is Necessary for Melanoma Growth

SIMPLE SUMMARY: Matrix metalloproteinases (MMPs) were considered as targets for the treatment of various cancers. However, initial trials using broad inhibitors to MMPs have failed, partly attributed to the contrasting functions of these proteases acting as tumor promoters and suppressors, among oth...

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Publicado en:Cancers (Basel)
Autores principales: Pach, Elke, Brinckmann, Jürgen, Rübsam, Matthias, Kümper, Maike, Mauch, Cornelia, Zigrino, Paola
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074311/
https://ncbi.nlm.nih.gov/pubmed/33924099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13081984
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