Effects of Macromolecular Crowding on Amyloid Beta (16–22) Aggregation Using Coarse-Grained Simulations

[Image: see text] To examine the effect of crowding on protein aggregation, discontinuous molecular dynamics (DMD) simulations combined with an intermediate resolution protein model, PRIME20, were applied to a peptide/crowder system. The systems contained 192 Aβ(16–22) peptides and crowders of diame...

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Detaylı Bibliyografya
Yayımlandı:J Phys Chem B
Asıl Yazarlar: Latshaw, David C., Cheon, Mookyung, Hall, Carol K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2014
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4254002/
https://ncbi.nlm.nih.gov/pubmed/25347801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp508970q
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