Arg287Gln VARIANT OF EPHX2 AND EPOXYEICOSATRIENOIC ACIDS ARE ASSOCIATED WITH INSULIN SENSITIVITY IN HUMANS

Epoxyeicosatrienoic acids (EETs) protect against the development of insulin resistance in rodents. EETs are hydrolyzed to less biologically active diols by soluble epoxide hydrolase (encoded for by EPHX2). Functional variants of EPHX2 encode for enzymes with increased (Lys55Arg) or decreased (Arg287...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Prostaglandins Other Lipid Mediat
Main Authors: Ramirez, Claudia E., Shuey, Megan M., Milne, Ginger L., Gilbert, Kimberly, Hui, Nian, Yu, Chang, Luther, James M., Brown, Nancy J.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253976/
https://ncbi.nlm.nih.gov/pubmed/25173047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2014.08.001
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares