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Arg287Gln VARIANT OF EPHX2 AND EPOXYEICOSATRIENOIC ACIDS ARE ASSOCIATED WITH INSULIN SENSITIVITY IN HUMANS
Epoxyeicosatrienoic acids (EETs) protect against the development of insulin resistance in rodents. EETs are hydrolyzed to less biologically active diols by soluble epoxide hydrolase (encoded for by EPHX2). Functional variants of EPHX2 encode for enzymes with increased (Lys55Arg) or decreased (Arg287...
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| Publicado no: | Prostaglandins Other Lipid Mediat |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4253976/ https://ncbi.nlm.nih.gov/pubmed/25173047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2014.08.001 |
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