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Association of gain-of-function EPHX2 polymorphism Lys55Arg with acute kidney injury following cardiac surgery

Twenty to thirty percent of patients undergoing cardiac surgery develop acute kidney injury (AKI). In mice, inhibition of soluble epoxide hydrolase (sEH) attenuates renal injury following ischemia-reperfusion. We tested the hypothesis that functional variants of EPHX2, encoding sEH, are associated w...

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Vydáno v:PLoS One
Hlavní autoři: Shuey, Megan M., Billings, Frederic T., Wei, Shouzou, Milne, Ginger L., Nian, Hui, Yu, Chang, Brown, Nancy J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5446112/
https://ncbi.nlm.nih.gov/pubmed/28552948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175292
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