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The carboxy-terminal domain of ROS1 is essential for 5-methylcytosine DNA glycosylase activity

Arabidopsis thaliana Repressor of silencing 1 (ROS1) is a multi-domain bifunctional DNA glycosylase/lyase, which excises 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) as well as thymine and 5-hydroxymethyluracil (i.e., the deamination products of 5mC and 5hmC) when paired with a guanine,...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Hong, Samuel, Hashimoto, Hideharu, Kow, Yoke Wah, Zhang, Xing, Cheng, Xiaodong
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253907/
https://ncbi.nlm.nih.gov/pubmed/25240767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.09.010
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