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Quantifying tumor heterogeneity in whole-genome and whole-exome sequencing data
Motivation: Most tumor samples are a heterogeneous mixture of cells, including admixture by normal (non-cancerous) cells and subpopulations of cancerous cells with different complements of somatic aberrations. This intra-tumor heterogeneity complicates the analysis of somatic aberrations in DNA sequ...
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| Udgivet i: | Bioinformatics |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4253833/ https://ncbi.nlm.nih.gov/pubmed/25297070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu651 |
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