Gli1 Activation and Protection Against Hepatic Encephalopathy is Suppressed by Circulating Transforming Growth Factor β1 in Mice

BACKGROUND & AIMS: Hepatic encephalopathy (HE) is a neurologic disorder that develops during liver failure. Few studies exist investigating systemic-central signaling during HE outside of inflammatory signaling. The transcription factor Gli1, which can be modulated by hedgehog signaling or trans...

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Publicat a:J Hepatol
Autors principals: McMillin, Matthew, Galindo, Cheryl, Pae, Hae Yong, Frampton, Gabriel, Patre, Pier Luigi Di, Quinn, Matthew, Whittington, Eric, DeMorrow, Sharon
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253574/
https://ncbi.nlm.nih.gov/pubmed/25046848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2014.07.015
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