Neuronal CCL2 is upregulated during hepatic encephalopathy and contributes to microglia activation and neurological decline

BACKGROUND: Acute liver failure leads to systemic complications with one of the most dangerous being a decline in neurological function, termed hepatic encephalopathy. Neurological dysfunction is exacerbated by an increase of toxic metabolites in the brain that lead to neuroinflammation. Following v...

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Hlavní autoři: McMillin, Matthew, Frampton, Gabriel, Thompson, Michelle, Galindo, Cheryl, Standeford, Holly, Whittington, Eric, Alpini, Gianfranco, DeMorrow, Sharon
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128607/
https://ncbi.nlm.nih.gov/pubmed/25012628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-121
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