Neuronal CCL2 is upregulated during hepatic encephalopathy and contributes to microglia activation and neurological decline

BACKGROUND: Acute liver failure leads to systemic complications with one of the most dangerous being a decline in neurological function, termed hepatic encephalopathy. Neurological dysfunction is exacerbated by an increase of toxic metabolites in the brain that lead to neuroinflammation. Following v...

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Main Authors: McMillin, Matthew, Frampton, Gabriel, Thompson, Michelle, Galindo, Cheryl, Standeford, Holly, Whittington, Eric, Alpini, Gianfranco, DeMorrow, Sharon
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4128607/
https://ncbi.nlm.nih.gov/pubmed/25012628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-11-121
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