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Hypoxia-inducible factors in regulation of immune responses in tumour microenvironment

Hypoxia is one of the hallmarks of the tumour microenvironment. It is the result of insufficient blood supply to support proliferating tumour cells. In response to hypoxia, the cellular machinery uses mechanisms whereby the low level of oxygen is sensed and counterbalanced by changing the transcript...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Immunology
Hauptverfasser: Kumar, Vinit, Gabrilovich, Dmitry I
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253499/
https://ncbi.nlm.nih.gov/pubmed/25196648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12380
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