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Hypoxia-inducible factor-1 in tumour angiogenesis
Hypoxia-inducible factor-1 (HIF-1), composed of HIF-α and HIF-β subunits, is a heterodimeric transcriptional activator. In response to hypoxia, stimulation of growth factors, and activation of oncogenes as well as carcinogens, HIF-1α is overexpressed and/or activated and targets those genes which ar...
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| Publicado no: | World J Gastroenterol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Baishideng Publishing Group Inc
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4656338/ https://ncbi.nlm.nih.gov/pubmed/15069703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v10.i8.1082 |
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