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Hypoxia-inducible factors in regulation of immune responses in tumour microenvironment

Hypoxia is one of the hallmarks of the tumour microenvironment. It is the result of insufficient blood supply to support proliferating tumour cells. In response to hypoxia, the cellular machinery uses mechanisms whereby the low level of oxygen is sensed and counterbalanced by changing the transcript...

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Опубликовано в: :Immunology
Главные авторы: Kumar, Vinit, Gabrilovich, Dmitry I
Формат: Artigo
Язык:Inglês
Опубликовано: BlackWell Publishing Ltd 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253499/
https://ncbi.nlm.nih.gov/pubmed/25196648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12380
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