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Hypoxia-inducible factors in regulation of immune responses in tumour microenvironment

Hypoxia is one of the hallmarks of the tumour microenvironment. It is the result of insufficient blood supply to support proliferating tumour cells. In response to hypoxia, the cellular machinery uses mechanisms whereby the low level of oxygen is sensed and counterbalanced by changing the transcript...

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Detalhes bibliográficos
Publicado no:Immunology
Principais autores: Kumar, Vinit, Gabrilovich, Dmitry I
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253499/
https://ncbi.nlm.nih.gov/pubmed/25196648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12380
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