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Radiolabeled Probes Targeting Hypoxia-Inducible Factor-1-Active Tumor Microenvironments
Because tumor cells grow rapidly and randomly, hypoxic regions arise from the lack of oxygen supply in solid tumors. Hypoxic regions in tumors are known to be resistant to chemotherapy and radiotherapy. Hypoxia-inducible factor-1 (HIF-1) expressed in hypoxic regions regulates the expression of genes...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4151590/ https://ncbi.nlm.nih.gov/pubmed/25215311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/165461 |
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