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Radiolabeled Probes Targeting Hypoxia-Inducible Factor-1-Active Tumor Microenvironments

Because tumor cells grow rapidly and randomly, hypoxic regions arise from the lack of oxygen supply in solid tumors. Hypoxic regions in tumors are known to be resistant to chemotherapy and radiotherapy. Hypoxia-inducible factor-1 (HIF-1) expressed in hypoxic regions regulates the expression of genes...

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Detaylı Bibliyografya
Asıl Yazarlar: Ueda, Masashi, Saji, Hideo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Hindawi Publishing Corporation 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151590/
https://ncbi.nlm.nih.gov/pubmed/25215311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/165461
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