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Epigenetic signatures of alcohol abuse and hepatitis infection during human hepatocarcinogenesis

Hepatocellular carcinoma (HCC) is the second most common cause of cancer deaths worldwide. Deregulated DNA methylation landscapes are ubiquitous in human cancers. Interpretation of epigenetic aberrations in HCC is confounded by multiple etiologic drivers and underlying cirrhosis. We globally profile...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Hlady, Ryan A., Tiedemann, Rochelle L., Puszyk, William, Zendejas, Ivan, Roberts, Lewis R., Choi, Jeong-Hyeon, Liu, Chen, Robertson, Keith D.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253444/
https://ncbi.nlm.nih.gov/pubmed/25294808
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