Linking DNA Methyltransferases (DNMTs) to Epigenetic Marks and Nucleosome Structure Genome-Wide in Human Tumor Cells

DNA methylation, mediated by the combined action of three DNA methyltransferases (DNMT1, DNMT3A, and DNMT3B), is essential for mammalian development and is a major contributor to cellular transformation. To elucidate how DNA methylation is targeted, we mapped the genome-wide localization of all DNMT...

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Detalhes bibliográficos
Main Authors: Jin, Bilian, Ernst, Jason, Tiedemann, Rochelle L., Xu, Hongyan, Sureshchandra, Suhas, Kellis, Manolis, Dalton, Stephen, Liu, Chen, Choi, Jeong-Hyeon, Robertson, Keith D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625945/
https://ncbi.nlm.nih.gov/pubmed/23177624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2012.10.017
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