Epigenetic signatures of alcohol abuse and hepatitis infection during human hepatocarcinogenesis

Hepatocellular carcinoma (HCC) is the second most common cause of cancer deaths worldwide. Deregulated DNA methylation landscapes are ubiquitous in human cancers. Interpretation of epigenetic aberrations in HCC is confounded by multiple etiologic drivers and underlying cirrhosis. We globally profile...

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Pubblicato in:Oncotarget
Autori principali: Hlady, Ryan A., Tiedemann, Rochelle L., Puszyk, William, Zendejas, Ivan, Roberts, Lewis R., Choi, Jeong-Hyeon, Liu, Chen, Robertson, Keith D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2014
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253444/
https://ncbi.nlm.nih.gov/pubmed/25294808
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