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HDX-MS Guided Drug Discovery: Small Molecules and Biopharmaceuticals
Hydrogen/deuterium exchange coupled with mass spectrometry (HDX-MS or DXMS) has emerged as an important tool for the development of small molecule therapeutics and biopharmaceuticals. Central to these advances have been improvements to automated HDX-MS platforms and software that allow for the rapid...
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| Pubblicato in: | Curr Opin Struct Biol |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4253076/ https://ncbi.nlm.nih.gov/pubmed/25179005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2014.08.007 |
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