Structural Insight into HIV-1 Restriction by MxB

The myxovirus resistance (Mx) proteins are interferon-induced dynamin GTPases that can inhibit a variety of viruses. Recently, MxB, but not MxA, was shown to restrict HIV-1 by an unknown mechanism that likely occurs in close proximity to the host cell nucleus and involves the viral capsid. Here, we...

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Publicat a:Cell Host Microbe
Autors principals: Fribourgh, Jennifer L., Nguyen, Henry C., Matreyek, Kenneth A., Alvarez, Frances Joan D., Summers, Brady J., Dewdney, Tamaria G., Aiken, Christopher, Zhang, Peijun, Engelman, Alan, Xiong, Yong
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252739/
https://ncbi.nlm.nih.gov/pubmed/25312384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2014.09.021
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