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.MxB Restricts HIV-1 by Targeting the Tri-hexamer Interface of the Viral Capsid

The human antiviral protein MxB is a restriction factor that fights HIV infection. Previous experiments have demonstrated that MxB targets the HIV capsid, a protein shell that protects the viral genome. To make the conical-shaped capsid, HIV CA proteins are organized into a lattice composed of hexam...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Smaga, Sarah Sierra, Xu, Chaoyi, Summers, Brady James, Digianantonio, Katherine Marie, Perilla, Juan R., Xiong, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7183857/
https://ncbi.nlm.nih.gov/pubmed/31155311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2019.04.015
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