The highly polymorphic cyclophilin A-binding loop in HIV-1 capsid modulates viral resistance to MxB

BACKGROUND: The human myxovirus-resistance protein B (MxB, also called Mx2) was recently reported to inhibit HIV-1 infection by impeding the nuclear import and integration of viral DNA. However, it is currently unknown whether there exist MxB-resistant HIV-1 strains in the infected individuals. Answ...

Full description

Saved in:
Bibliographic Details
Published in:Retrovirology
Main Authors: Liu, Zhenlong, Pan, Qinghua, Liang, Zhibin, Qiao, Wentao, Cen, Shan, Liang, Chen
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
Subjects:
Short Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300040/
https://ncbi.nlm.nih.gov/pubmed/25571928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-014-0129-1
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items