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The highly polymorphic cyclophilin A-binding loop in HIV-1 capsid modulates viral resistance to MxB
BACKGROUND: The human myxovirus-resistance protein B (MxB, also called Mx2) was recently reported to inhibit HIV-1 infection by impeding the nuclear import and integration of viral DNA. However, it is currently unknown whether there exist MxB-resistant HIV-1 strains in the infected individuals. Answ...
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| Publié dans: | Retrovirology |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4300040/ https://ncbi.nlm.nih.gov/pubmed/25571928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-014-0129-1 |
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