HIV-1 resists MxB inhibition of viral Rev protein

The interferon-inducible myxovirus resistance B (MxB) protein has been reported to inhibit HIV-1 and herpesviruses by blocking the nuclear import of viral DNA. Here, we report a new antiviral mechanism in which MxB restricts the nuclear import of HIV-1 regulatory protein Rev, and as a result, dimini...

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Vydáno v:Emerg Microbes Infect
Hlavní autoři: Wang, Zhen, Chai, Keli, Liu, Qian, Yi, Dong-Rong, Pan, Qinghua, Huang, Yu, Tan, Juan, Qiao, Wentao, Guo, Fei, Cen, Shan, Liang, Chen
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7534208/
https://ncbi.nlm.nih.gov/pubmed/32873191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/22221751.2020.1818633
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