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GROWTH HORMONE ABOLISHES BENEFICIAL EFFECTS OF CALORIE RESTRICTION IN LONG-LIVED AMES DWARF MICE
Disruption of the growth hormone (GH) axis promotes longevity and delays aging. In contrast, GH over-expression may lead to accelerated aging and shorter life. Calorie restriction (CR) improves insulin sensitivity and may extend lifespan. Long-lived Ames dwarf (df/df) mice have additional extension...
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| Vydáno v: | Exp Gerontol |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4252511/ https://ncbi.nlm.nih.gov/pubmed/25152388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2014.08.010 |
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