The effect of calorie restriction on insulin signaling in skeletal muscle and adipose tissue of Ames dwarf mice

Long-living Ames dwarf (df/df) mice are homozygous for a mutation of the Prop1(df) gene. As a result, mice are deficient in growth hormone (GH), prolactin (PRL) and thyrotropin (TSH). In spite of the hormonal deficiencies, df/df mice live significantly longer and healthier lives compared to their wi...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Wiesenborn, Denise S., Menon, Vinal, Zhi, Xu, Do, Andrew, Gesing, Adam, Wang, Zhihui, Bartke, Andrzej, Altomare, Deborah A., Masternak, Michal M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247389/
https://ncbi.nlm.nih.gov/pubmed/25411241
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