Distinct Roles for Hematopoietic and Extra-Hematopoietic Sphingosine Kinase-1 in Inflammatory Bowel Disease

Sphingosine kinase 1 (SK1), one of two SK enzymes, is highly regulated and has been shown to act as a focal point for the action of many growth factors and cytokines. SK1 leads to generation of sphingosine-1-phosphate (S1P) and potentially the activation of S1P receptors to mediate biologic effects....

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Snider, Ashley J., Ali, Wahida H., Sticca, Jonathan A., Coant, Nicolas, Ghaleb, Amr M., Kawamori, Toshihiko, Yang, Vincent W., Hannun, Yusuf A., Obeid, Lina M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4252067/
https://ncbi.nlm.nih.gov/pubmed/25460165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113998
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi