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Loss of neutral ceramidase increases inflammation in a mouse model of inflammatory bowel disease
Sphingolipids are emerging as important mediators of immune and inflammatory responses. We have previously demonstrated that sphingosine-1-phosphate (S1P) and its synthetic enzyme sphingosine kinase-1 (SK1) play an important role in inflammatory bowel disease. S1P generation is dependent on SK phosp...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3661865/ https://ncbi.nlm.nih.gov/pubmed/22940715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2012.08.003 |
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