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A role for sphingosine kinase 1 in dextran sulfate sodium-induced colitis
The bioactive lipid sphingosine-1-phosphate (S1P) is emerging as an important mediator of immune and inflammatory responses. S1P formation is catalyzed by sphingosine kinase (SK), of which the SK1 isoenzyme is activated by tumor necrosis alpha (TNF-α). SK1 has been shown to be required for mediating...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The Federation of American Societies for Experimental Biology
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2626622/ https://ncbi.nlm.nih.gov/pubmed/18815359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-118109 |
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