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Role for sphingosine kinase 1 in colon carcinogenesis
Sphingosine kinase 1 (SphK1) phosphorylates sphingosine to form sphingosine-1-phosphate (S1P) and is a critical regulator of sphingolipid-mediated functions. Cell-based studies suggest a tumor-promoting function for the SphK1/S1P pathway. Also, our previous studies implicated the SphK1/S1P pathway i...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Federation of American Societies for Experimental Biology
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2630788/ https://ncbi.nlm.nih.gov/pubmed/18824518 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-117572 |
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