Sphingosine Kinase 1 expression in peritoneal macrophages is required for colon carcinogenesis

Accumulating evidence suggests that the sphingosine kinase 1 (SphK1)/sphingosine 1-phosphate (S1P) pathway plays a pivotal role in colon carcinogenesis. Our previous studies indicate that the SphK1/S1P pathway mediates colon carcinogenesis at least by regulating cyclooxygenase 2 (COX-2) expression a...

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Detalhes bibliográficos
Publicado no:Carcinogenesis
Main Authors: Furuya, Hideki, Tamashiro, Paulette M, Shimizu, Yoshiko, Iino, Kayoko, Peres, Rafael, Chen, Runpu, Sun, Yijun, Hannun, Yusuf A, Obeid, Lina M, Kawamori, Toshihiko
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Carcinogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5862304/
https://ncbi.nlm.nih.gov/pubmed/29028945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgx104
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