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Structural and protein interaction effects of hypertrophic and dilated cardiomyopathic mutations in alpha-tropomyosin
The potential alterations to structure and associations with thin filament proteins caused by the dilated cardiomyopathy (DCM) associated tropomyosin (Tm) mutants E40K and E54K, and the hypertrophic cardiomyopathy (HCM) associated Tm mutants E62Q and L185R, were investigated. In order to ascertain w...
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| Veröffentlicht in: | Front Physiol |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4251307/ https://ncbi.nlm.nih.gov/pubmed/25520664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00460 |
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