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Mitochondrial DNA Damage as a Peripheral Biomarker for Mitochondrial Toxin Exposure in Rats

Demonstrating or verifying a current or past exposure to an environmental mitochondrial toxin or toxicant is extraordinarily difficult. Thus, there is a pressing need to develop a biomarker for exposure to environmental mitochondrial inhibitors. Rotenone, an environmental toxicant, is a potent inhib...

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Détails bibliographiques
Publié dans:Toxicol Sci
Auteurs principaux: Sanders, Laurie H., Howlett, Evan H., McCoy, Jennifer, Greenamyre, J. Timothy
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250844/
https://ncbi.nlm.nih.gov/pubmed/25237061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu185
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