Differential impairment of aspirin-dependent platelet cyclooxygenase acetylation by nonsteroidal antiinflammatory drugs

The cardiovascular safety of nonsteroidal antiinflammatory drugs (NSAIDs) may be influenced by interactions with antiplatelet doses of aspirin. We sought to quantitate precisely the propensity of commonly consumed NSAIDs—ibuprofen, naproxen, and celecoxib—to cause a drug–drug interaction with aspiri...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Li, Xuanwen, Fries, Susanne, Li, Ruizhi, Lawson, John A., Propert, Kathleen J., Diamond, Scott L., Blair, Ian A., FitzGerald, Garret A., Grosser, Tilo
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250103/
https://ncbi.nlm.nih.gov/pubmed/25385584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406997111
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