Differential impairment of aspirin-dependent platelet cyclooxygenase acetylation by nonsteroidal antiinflammatory drugs

The cardiovascular safety of nonsteroidal antiinflammatory drugs (NSAIDs) may be influenced by interactions with antiplatelet doses of aspirin. We sought to quantitate precisely the propensity of commonly consumed NSAIDs—ibuprofen, naproxen, and celecoxib—to cause a drug–drug interaction with aspiri...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Li, Xuanwen, Fries, Susanne, Li, Ruizhi, Lawson, John A., Propert, Kathleen J., Diamond, Scott L., Blair, Ian A., FitzGerald, Garret A., Grosser, Tilo
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250103/
https://ncbi.nlm.nih.gov/pubmed/25385584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406997111
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