Differential impairment of aspirin-dependent platelet cyclooxygenase acetylation by nonsteroidal antiinflammatory drugs

The cardiovascular safety of nonsteroidal antiinflammatory drugs (NSAIDs) may be influenced by interactions with antiplatelet doses of aspirin. We sought to quantitate precisely the propensity of commonly consumed NSAIDs—ibuprofen, naproxen, and celecoxib—to cause a drug–drug interaction with aspiri...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Li, Xuanwen, Fries, Susanne, Li, Ruizhi, Lawson, John A., Propert, Kathleen J., Diamond, Scott L., Blair, Ian A., FitzGerald, Garret A., Grosser, Tilo
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2014
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250103/
https://ncbi.nlm.nih.gov/pubmed/25385584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406997111
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