The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy

Stromal cells within the tumor microenvironment are essential for tumor progression and metastasis. Surprisingly little is known about the factors that drive the transcriptional reprogramming of stromal cells within tumors. We report that the transcriptional regulator Heat-Shock Factor 1 (HSF1) is f...

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Bibliografische gegevens
Gepubliceerd in:Cell
Hoofdauteurs: Scherz-Shouval, Ruth, Santagata, Sandro, Mendillo, Marc L., Sholl, Lynette M., Ben-Aharon, Irit, Beck, Andrew H., Dias-Santagata, Dora, Koeva, Martina, Stemmer, Salomon M., Whitesell, Luke, Lindquist, Susan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249939/
https://ncbi.nlm.nih.gov/pubmed/25083868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.05.045
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