The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy

Stromal cells within the tumor microenvironment are essential for tumor progression and metastasis. Surprisingly little is known about the factors that drive the transcriptional reprogramming of stromal cells within tumors. We report that the transcriptional regulator Heat-Shock Factor 1 (HSF1) is f...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Scherz-Shouval, Ruth, Santagata, Sandro, Mendillo, Marc L., Sholl, Lynette M., Ben-Aharon, Irit, Beck, Andrew H., Dias-Santagata, Dora, Koeva, Martina, Stemmer, Salomon M., Whitesell, Luke, Lindquist, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249939/
https://ncbi.nlm.nih.gov/pubmed/25083868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.05.045
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