The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy

Stromal cells within the tumor microenvironment are essential for tumor progression and metastasis. Surprisingly little is known about the factors that drive the transcriptional reprogramming of stromal cells within tumors. We report that the transcriptional regulator Heat-Shock Factor 1 (HSF1) is f...

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Pubblicato in:Cell
Autori principali: Scherz-Shouval, Ruth, Santagata, Sandro, Mendillo, Marc L., Sholl, Lynette M., Ben-Aharon, Irit, Beck, Andrew H., Dias-Santagata, Dora, Koeva, Martina, Stemmer, Salomon M., Whitesell, Luke, Lindquist, Susan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249939/
https://ncbi.nlm.nih.gov/pubmed/25083868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.05.045
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