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PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors
Malignant Peripheral Nerve Sheath Tumors (MPNSTs) represent a group of highly aggressive soft tissue sarcomas that may occur sporadically, in association with neurofibromatosis type I (NF1-), or after radiotherapy(1–3). Using comprehensive genomic approaches, we identified loss-of-function (LOF) som...
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| Veröffentlicht in: | Nat Genet |
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| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4249650/ https://ncbi.nlm.nih.gov/pubmed/25240281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3095 |
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