Combined targeting of mTOR and c-MET signaling pathways for effective management of epithelioid sarcoma

BACKGROUND: Epithelioid sarcoma (EpS) is a high-grade malignant soft-tissue sarcoma characterized by local recurrences and distant metastases. Effective treatments for EpS have not been established and thus novel therapeutic approaches against EpS are urgently required. mTOR inhibitors exert antitum...

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Détails bibliographiques
Publié dans:Mol Cancer
Auteurs principaux: Imura, Yoshinori, Yasui, Hirohiko, Outani, Hidetatsu, Wakamatsu, Toru, Hamada, Kenichiro, Nakai, Takaaki, Yamada, Shutaro, Myoui, Akira, Araki, Nobuhito, Ueda, Takafumi, Itoh, Kazuyuki, Yoshikawa, Hideki, Naka, Norifumi
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249599/
https://ncbi.nlm.nih.gov/pubmed/25098767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-185
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