Combined targeting of mTOR and c-MET signaling pathways for effective management of epithelioid sarcoma

BACKGROUND: Epithelioid sarcoma (EpS) is a high-grade malignant soft-tissue sarcoma characterized by local recurrences and distant metastases. Effective treatments for EpS have not been established and thus novel therapeutic approaches against EpS are urgently required. mTOR inhibitors exert antitum...

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Bibliografiske detaljer
Udgivet i:Mol Cancer
Main Authors: Imura, Yoshinori, Yasui, Hirohiko, Outani, Hidetatsu, Wakamatsu, Toru, Hamada, Kenichiro, Nakai, Takaaki, Yamada, Shutaro, Myoui, Akira, Araki, Nobuhito, Ueda, Takafumi, Itoh, Kazuyuki, Yoshikawa, Hideki, Naka, Norifumi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249599/
https://ncbi.nlm.nih.gov/pubmed/25098767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-185
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