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Combined targeting of mTOR and c-MET signaling pathways for effective management of epithelioid sarcoma

BACKGROUND: Epithelioid sarcoma (EpS) is a high-grade malignant soft-tissue sarcoma characterized by local recurrences and distant metastases. Effective treatments for EpS have not been established and thus novel therapeutic approaches against EpS are urgently required. mTOR inhibitors exert antitum...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Imura, Yoshinori, Yasui, Hirohiko, Outani, Hidetatsu, Wakamatsu, Toru, Hamada, Kenichiro, Nakai, Takaaki, Yamada, Shutaro, Myoui, Akira, Araki, Nobuhito, Ueda, Takafumi, Itoh, Kazuyuki, Yoshikawa, Hideki, Naka, Norifumi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249599/
https://ncbi.nlm.nih.gov/pubmed/25098767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-185
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