Therapeutic potential of TAS-115 via c-MET and PDGFRα signal inhibition for synovial sarcoma

BACKGROUND: The prognosis of synovial sarcoma (SS), an aggressive soft tissue sarcoma, remains poor. We previously reported that c-MET or platelet-derived growth factor receptor α (PDGFRα) signalling pathway is related to SS progression based upon the findings of phospho-receptor tyrosine kinase (RT...

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Bibliografiske detaljer
Udgivet i:BMC Cancer
Main Authors: Yamada, Shutaro, Imura, Yoshinori, Nakai, Takaaki, Nakai, Sho, Yasuda, Naohiro, Kaneko, Keiko, Outani, Hidetatsu, Takenaka, Satoshi, Hamada, Kenichiro, Myoui, Akira, Araki, Nobuhito, Ueda, Takafumi, Itoh, Kazuyuki, Yoshikawa, Hideki, Naka, Norifumi
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434537/
https://ncbi.nlm.nih.gov/pubmed/28511645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3324-3
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