Heterogeneity of mprF Sequences in Methicillin-Resistant Staphylococcus aureus Clinical Isolates: Role in Cross-Resistance between Daptomycin and Host Defense Antimicrobial Peptides

Over the past several years, single-nucleotide polymorphisms (SNPs) within the mprF open reading frame (ORF) have been proposed to be associated with a gain-of-function phenotype in terms of daptomycin (DAP) nonsusceptibility (referred to as daptomycin resistance [DAP-R] herein for ease of presentat...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Bayer, Arnold S., Mishra, Nagendra N., Sakoulas, George, Nonejuie, Poochit, Nast, Cynthia C., Pogliano, Joseph, Chen, Kuan-Tsen, Ellison, Steven N., Yeaman, Michael R., Yang, Soo-Jin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249560/
https://ncbi.nlm.nih.gov/pubmed/25288091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03422-14
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky