Reduced Susceptibility to Host-Defense Cationic Peptides and Daptomycin Coemerge in Methicillin-Resistant Staphylococcus aureus From Daptomycin-Naive Bacteremic Patients

Background. We hypothesized that, for methicillin-resistant Staphylococcus aureus (MRSA), in vitro daptomycin susceptibility could be influenced by exposures to endogenous host defense peptides (HDPs) prior to clinical exposure to daptomycin. Methods. Two endovascular HDPs were used: thrombin-induce...

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Bibliografiske detaljer
Main Authors: Mishra, Nagendra N., Bayer, Arnold S., Moise, Pamela A., Yeaman, Michael R., Sakoulas, George
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2012
Fag:
Major Articles and Brief Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3448966/
https://ncbi.nlm.nih.gov/pubmed/22904338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis482
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