Role of Pfmdr1 in In Vitro Plasmodium falciparum Susceptibility to Chloroquine, Quinine, Monodesethylamodiaquine, Mefloquine, Lumefantrine, and Dihydroartemisinin

The involvement of Pfmdr1 (Plasmodium falciparum multidrug resistance 1) polymorphisms in antimalarial drug resistance is still debated. Here, we evaluate the association between polymorphisms in Pfmdr1 (N86Y, Y184F, S1034C, N1042D, and D1246Y) and Pfcrt (K76T) and in vitro responses to chloroquine...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Wurtz, Nathalie, Fall, Bécaye, Pascual, Aurélie, Fall, Mansour, Baret, Eric, Camara, Cheikhou, Nakoulima, Aminata, Diatta, Bakary, Fall, Khadidiatou Ba, Mbaye, Pape Saliou, Diémé, Yaya, Bercion, Raymond, Wade, Boubacar, Pradines, Bruno
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2014
Konular:
Mechanisms of Resistance
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249527/
https://ncbi.nlm.nih.gov/pubmed/25199781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03494-14
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